August 5, 2016 — Lawsuits have been filed by seven men who say the erectile dysfunction drug Cialis caused them to develop skin cancer.
The Indianapolis Business Journal reports that the lawsuits were filed by men in Ohio, Illinois, Texas, and other states.
They all accuse Eli Lilly & Co. of failing to warn about a “significant risk of exacerbating melanoma” on the label for Cialis.
In recent years, several studies have found higher rates of melanoma (skin cancer) among men who used erectile dysfunction drugs like Viagra and Cialis. In one study, men on Viagra were 84% more likely to develop melanoma.
These drugs work by inhibiting an enzyme called PDE5, which is also inhibited by melanoma. Other studies have found that low levels of PDE5 increase the aggressiveness of melanoma.
Some researchers believe men who can afford Viagra and Cialis are also more likely to spend time outdoors. The problem with this argument is that sun exposure is associated with all types of skin cancer, but Viagra and Cialis are only associated with melanoma.
In April 2016, judges centralized 14 Viagra melanoma lawsuits into a Multi-District Litigation (MDL No. 2691) in the U.S. District Court for the Northern District of California. As of mid-July, there were 80 lawsuits pending in the MDL.
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